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NeoPerfuse

Solution architecture

Solution / Technology

NeoPerfuse combines wavelength-engineered multi-channel optical sensing with an explainable AI-based Signal Quality Index to make neonatal oxygenation and perfusion signals more trustworthy.

System architecture

Explainable AI-SQIgood vs problematicReliableCheck contact
  1. Step 1

    Skin-friendly patch

    A neonatal-compatible patch designed for fragile skin, small extremities, and difficult placement.

  2. Step 2

    Multi-channel optical signals

    Selected channels target SpO₂ baseline, tissue oxygenation, perfusion context, and water/contact effects.

  3. Step 3

    Explainable AI-SQI

    AI evaluates each channel and time segment to reject artifacts and classify likely failure modes.

  4. Step 4

    Signal confidence + reason

    The output shows whether the optical signal is trustworthy and why it may be unreliable.

Neonatal-compatible sensor concept

A skin-friendly sensor head or patch designed for very small extremities and fragile neonatal skin. The design objective is fast placement, stable optical coupling, low-burden use, and compatibility with delivery-room and NICU workflows.

Fragile-skin compatible design

Aims to reduce placement burden on delicate neonatal skin.

Small-extremity form factor

Designed around the constraints of preterm anatomy.

Fast and reproducible placement

Supports delivery-room and NICU workflows under time pressure.

Stable optical coupling

Focused on difficult wet-skin, contact, and motion conditions.

Multispectral optical acquisition

The system acquires optical raw signals across multiple wavelength channels. Additional NIR/SWIR-adjacent channels may support perfusion sensitivity, artifact assessment, and signal-quality discrimination rather than being presented as a broad claim of superior SpO2 accuracy.

Conventional optical channels

Reference-compatible optical acquisition concepts.

Additional multispectral channels

Exploratory wavelength channels for signal-quality discrimination.

Perfusion-sensitive analysis

Designed to evaluate pulsatility and low-perfusion behavior.

Artifact and contact-quality assessment

Aims to make signal reliability more transparent.

AI-based Signal Quality Index

The AI component is designed as clinically explainable trust logic rather than a black-box oxygen-value estimator. It evaluates whether the optical information is interpretable and may classify why a signal is unreliable.

Motion artifact

Movement affecting waveform reliability.

Low perfusion

Weak pulsatility or poor peripheral signal.

Poor sensor contact

Suboptimal optical coupling.

Wet skin

Moisture affecting sensor-skin interface.

Sensor displacement

Patch movement or misalignment.

Insufficient pulsatility

Limited interpretable waveform content.

Confidence-aware clinical output

Confidence-aware output

Signal qualityHigh
Motion likelihoodLow

Signal confidence

High / Medium / Low

Likely failure mode

Motion / Low perfusion / Poor contact / Wet skin / Displacement

Suggested interpretation

Signal interpretable / not interpretable / check contact / prioritize reference monitoring

Collaboration

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