Neonatal transition and oxygenation monitoring
Clinical context for the first minutes after birth.
Scientific foundation
Scientific Papers, Publications & Patents
NeoPerfuse builds on optical sensing, multispectral photodetection, neonatal monitoring, signal-quality assessment, and translational medtech development.
Disclosure note
Some publications, patent details, and ownership/licensing information are placeholders and must be confirmed before public disclosure.
Scientific foundation
The scientific basis of NeoPerfuse includes neonatal transition monitoring, pulse oximetry limitations under difficult conditions, multispectral optical sensing, NIR/SWIR-adjacent detector concepts, and AI-based signal-quality assessment.
Preductal pulse oximetry and early SpO2 targets
Reference workflows and target ranges subject to local protocols.
Motion and low-perfusion optical signal artifacts
Known limitations affecting interpretability.
Multispectral optical sensing
Additional spectral information for signal-quality assessment.
NIR/SWIR photodetector research
Detector concepts informing future multispectral exploration.
Explainable AI for signal-quality assessment
Clinically understandable SQI and failure-mode logic.
Selected publications
High-performance solution-processed TIIG-based polymer photodetector with detectivity across scalable SWIR applications
- Authors
- R. Holfeuer, M. Comi, S. Schroeder, M. Bouraoui, J. Hofmann, R. Hooijer, E. Aydin, A. Hartschuh, M. Al-Hashimi, A. YousefiAmin, T. Ameri
- Year
- 2026
- Type
- Journal article, Materials Horizons
- Status
- Published, Advance Article
Reports a solution-processed organic NIR/SWIR photodetector concept relevant to detector-level optical sensing research.
Source information
- Source
- pubs.rsc.org
- Access
- External source link
DeliverO₂: Time Trajectory and Oxygenation Strategies for Very Preterm Infants in the Delivery Room
- Authors
- A. Y. Amin, J. W. Hesser, C. Gille, C. E. Schwarz
- Year
- 2026
- Type
- Conference Poster, GNPI Annual Meeting 2026
- Status
- Conference poster
This exploratory delivery-room study investigates whether the Oxygenation Ratio (SpO₂/FiO₂) can help distinguish early oxygenation patterns in very preterm infants and support more actionable oxygen titration during the first minutes after birth.
very preterm infants · delivery room · oxygenation · SpO₂/FiO₂ · bedside decision support
Related publication source links
Trap Healing for High-Performance Low-Voltage Polymer Transistors and Solution-Based Analog Amplifiers on Foil
External citation record for an organic electronics publication.
- Authors
- V. Pecunia, M. Nikolka, A. Sou, I. Nasrallah, A. Y. Amin, I. McCulloch, H. Sirringhaus
- Year
- 2017
- Venue
- Advanced Materials
- Source
- Google Scholar
- Record ID
- tW5qqI8AAAAJ:9yKSN-GCB0IC
Solution-processed single-crystalline organic transistors on patterned ultrathin gate insulators
External citation record for a solution-processed organic transistor publication.
- Authors
- J. Tsurumi, A. Yousefi Amin, T. Okamoto, C. Mitsui, K. Takimiya, H. Matsui, M. Halik, J. Takeya
- Year
- 2014
- Venue
- Organic Electronics
- Source
- Google Scholar
- Record ID
- tW5qqI8AAAAJ:Tyk-4Ss8FVUC
Low-Voltage Self-Assembled Monolayer Field-Effect Transistors on Flexible Substrates
External citation record for a flexible electronics publication.
- Authors
- T. Schmaltz, A. Y. Amin, A. Khassanov, T. Meyer-Friedrichsen, H.-G. Steinrueck, A. Magerl, J. J. Segura, K. Voitchovsky, F. Stellacci, M. Halik
- Year
- 2013
- Venue
- Advanced Materials
- Source
- Google Scholar
- Record ID
- tW5qqI8AAAAJ:u5HHmVD_uO8C
Printed CsMg-ZnO ETLs achieve over 9% efficiency in PbS quantum dot solar cells
External citation record for a printed quantum-dot solar cell publication.
- Authors
- R. Holfeuer, C. Maheu, H. Illner, R. Hoojier, H. Balakrishnan, B. Maerz, S. Lotfi, H. Sezen, K. Mueller-Caspary, T. Bein, J. P. Hofmann, T. Ameri, A. Hartschuh, A. YousefiAmin
- Year
- 2025
- Venue
- Materials Today Energy
- Source
- Google Scholar
- Record ID
- zyyKsB0AAAAJ:hqOjcs7Dif8C
Fully printed infrared photodetectors from PbS nanocrystals with perovskite ligands
External citation record for an infrared photodetector publication.
- Authors
- A. YousefiAmin, N. A. Killilea, M. Sytnyk, P. Maisch, K. C. Tam, H.-J. Egelhaaf, S. Langner, T. Stubhan, C. J. Brabec, T. Rejek, M. Halik, K. Poulsen, J. Niehaus, A. Koeck, W. Heiss
- Year
- 2019
- Venue
- ACS Nano
- Source
- Google Scholar
- Record ID
- zyyKsB0AAAAJ:IjCSPb-OGe4C
Patents and intellectual property
Patent application: EP4407685A1
- Status
- Patent application - external patent record
- Technology area
- Spectrally selective / multispectral detector elements
This patent family is treated as potential background IP for detector-level differentiation. It should not be described as already protecting the complete neonatal application, AI-based Signal Quality Index, or medical workflow claim unless confirmed by patent counsel.
View patent applicationA final legal Freedom-to-Operate assessment is still pending. Public wording should remain cautious until ownership, assignee, legal status, licensing path, and right-to-commercialize are confirmed.
Planned project-specific IP areas
Neonatal multispectral sensor-head architecture
AI-based Signal Quality Index with failure-mode classification
Confidence-gated output logic
Neonatal calibration and dataset workflow
Detector packaging and encapsulation for fragile neonatal skin
Clinical workflow integration around signal interpretability
Freedom-to-operate focus areas
Motion-tolerant pulse oximetry
Low-perfusion SpO2 algorithms
Multi-wavelength SpO2 calculation
Signal-quality indices
Alarm and display logic
Closed-loop oxygen-control interfaces
NeoPerfuse should avoid broad claims around general pulse oximetry, standard red/IR SpO2 calculation, or autonomous oxygen therapy. The safer differentiation is neonatal-specific multispectral signal confidence, failure-mode classification, fragile-skin optical architecture, and confidence-gated output.
Collaboration
Scientific or IP collaboration
We welcome discussion with academic, clinical, technology-transfer, and medtech partners.