Skip to main content
NeoPerfuse

Clinical context

Clinical Need

Preterm newborns require rapid and trustworthy oxygenation and perfusion assessment during a highly dynamic physiological transition after birth.

Why early optical monitoring can be difficult

During the first minutes after birth, clinicians work under time pressure while the newborn may have low peripheral perfusion, movement, wet skin, fragile skin, and very small extremities. These conditions can make optical oxygenation and perfusion signals difficult to acquire or interpret.

  1. Birth

    Initial transition

    Standard neonatal assessment begins, while optical oxygenation and perfusion signals may not yet be stable.

  2. 3 minutes

    Early signal window

    Optical signals may still be delayed or unstable due to low perfusion, motion, wet skin, or poor contact.

  3. 10 minutes

    Stabilization window

    Teams need confidence that optical trends reflect physiology rather than artifact or sensor failure.

  4. Early NICU

    Ongoing care

    Signal trustworthiness remains important during ongoing fragile monitoring and sensor repositioning.

The challenge is not the absence of monitoring. The challenge is uncertainty: is the optical signal clinically trustworthy, or is it affected by artifact?

Current standard of care

Current neonatal monitoring relies on ECG-based heart-rate assessment, preductal pulse oximetry, and integrated patient-monitoring systems. NeoPerfuse respects this standard of care and focuses on the residual gap: earlier trustworthy optical oxygenation/perfusion information under difficult preterm-transition conditions.

Clinical users

Neonatologists

Rapid interpretation of oxygenation and perfusion status.

Neonatal nurses

Reduced repeated sensor repositioning and clearer signal feedback.

Delivery-room teams

Faster confidence during early transition.

NICU teams

Improved transparency in unstable monitoring windows.

Clinical researchers

Structured signal-quality and workflow data.

Unmet need statement

NeoPerfuse addresses signal delay, instability, and uncertainty in the first critical minutes of preterm neonatal care. The aim is not to replace established monitors, but to make optical signal reliability more explicit.

Collaboration

Interested in validating the clinical need?

Become a Clinical Partner